Development of CT texture analysis in COPD and association with visual scoring and DLco

<p>  </p> <p><strong>Objectives</strong></p> <ul> <li>To determine if CT texture features, such as GLCM and FD, can differentiate patients with COPD from healthy volunteers, and are related to lung function</li> <li>To determine if CT texture features are association with qualitative visual scoring</li> <li>To determine if CT texture features are significantly associated with COPD outcomes, independent of qualitative scoring and standard quantitative CT emphysema measurements</li> </ul> <p><strong>Hypothesis</strong></p> <ul> <li>CT texture features can be developed to objectively aid in quantifying the severity of emphysema, and may provide information complementary to qualitative visual assessment</li> </ul><p></p>