OncoProfiler - A Multi-Cancer Early Detection (MCED) Assay

Laser fabricated SERS nanosensors, OncoProfiler, demonstrated detection sensitivity that sufficient to sense trace amount of tumor-associated content from unprocessed plasma or buffy coat. OncoProfiler enabled the discovery of new biomarkers for cancer detection, which are undetectable with conventional bioassay-based methods. A single test with OncoProfiler could sense multiple biomarkers, which provides high diagnostic accuracy as well as a holistic representation of the spatial and temporal heterogeneity of a tumor. Due to high sensitivity, OncoProfiler has the potential to lead to a non-invasive blood based Multi-Cancer Early Detection (MCED) assay meant for cancer screening and therapeutic monitoring.