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Nutritional considerations to inform nutritional safety assessments of foods derived from cellular agriculture: A scoping review protocol

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posted on 2025-10-22, 20:51 authored by Karima Benkhedda, Matthew D. Parrott, Stephanie K. NishiStephanie K. Nishi, Vincent C.H. Wong, Laura Kenney, Chao-Wu Xiao, Atiq Rehman, Subhadeep Chakrabarti, Mélanie Whiteside
<p dir="ltr">Cellular agriculture is the production of meat, milk, eggs, seafood, and other products and ingredients from cell cultures rather than from farmed animals. It is an emerging field in food innovation that has gained attention of the scientific community, food industry, and regulators around the world. This scoping review aims to summarize existing knowledge on cell-cultured food products, focusing on key aspects that impact their nutritional quality and identifying knowledge gaps in this area. Relevant publications will be identified from electronic databases and the grey literature. This review will include scientific publications (peer-reviewed journal articles; reports from regulatory, scientific, or non-governmental bodies) that report or discuss nutritional considerations concerning cell-cultured food products derived from plant or animal cells. Based on pre-determined inclusion and exclusion criteria, records from scientific databases will be screened and selected by two independent reviewers, while records from grey literature will be screened by one reviewer. Data from the included references will be extracted by one reviewer using pre-piloted extraction templates, and verified by a second reviewer. The findings will inform and strengthen Health Canada’s nutritional assessments of novel foods derived from cellular agriculture. Identified research gaps will provide opportunities for future research in this area.</p>

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