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A Study of High Frequency Ultrasound Scattering from Non-nucleated Biological Specimens

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journal contribution
posted on 2022-11-02, 14:33 authored by Omar Falou, Ralph E. Baddour, George Nathanael, Gregory J. Czarnota, Carl KumaradasCarl Kumaradas, Michael KoliosMichael Kolios
The high frequency backscatter from cells with a nucleus to cell volume ratio of 0.50 cannot be adequately modeled as a homogeneous sphere. It was hypothesized that the cytoplasm of such cells is of fluid nature. This work attempts to model the ultrasound backscatter (10–62 MHz) from some non-nucleated biological specimens. This was done by measuring the backscatter response from individual sea urchin oocytes and comparing it to theoretical predictions in both the time and frequency domains. A good agreement was found between the experimental and theoretical results suggesting that the non-nucleated oocytes are of fluid nature.